RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
mir-675
RNA ID
MI0004123
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
microarray analyses; bioinformatics analyses
Target
TGFBR1
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
30953355
Title
A novel mechanism of Smads/miR-675/TGFbetaR1 axis modulating the proliferation and remodeling of mouse cardiac fibroblasts
Year
2019
Function
miR-675 targets TGF-betaR1 to attenuate TGF-beta1-induced mouse cardiac fibroblast (CF) remodeling and proliferation.